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1

A Roadmap to Safe, Efficient, and Stable Lentivirus-Mediated Gene Therapy with Hematopoietic Cell Transplantation

Anton Neschadim, J. Andrea McCart, Armand Keating, Jeffrey A. Medin

Journal:

Biology of Blood and Marrow Transplantation

Year:

2007

Language:

english

File:

PDF, 578 KB

english, 2007

2

Relaxin-3 and receptors in the human and rhesus brain and reproductive tissues

Josh D. Silvertown, Anton Neschadim, Hsueh-Ning Liu, Patrick Shannon, Jagdeep S. Walia, Jessica C.H. Kao, Janice Robertson, Alastair J.S. Summerlee, Jeffrey A. Medin

Journal:

Regulatory Peptides

Year:

2010

Language:

english

File:

PDF, 1.78 MB

english, 2010

3

87. Outcomes of testing Lentivector-mediated Gene Therapy for Farber Disease in Non-Human Primates

Jeffrey Medin, Jagdeep Walia, Anton Neschadim, Xin Fan, Melissa Madden, Fred Cheung, David Jaffray, Thierry Levade, Roscoe Brady, J. Andrea McCart

Journal:

Molecular Genetics and Metabolism

Year:

2009

Language:

english

File:

PDF, 42 KB

english, 2009

4

Bystander killing of malignant cells via the delivery of engineered thymidine-active deoxycytidine kinase for suicide gene therapy of cancer

Neschadim, A, Wang, J C M, Lavie, A, Medin, J A

Journal:

Cancer Gene Therapy

Year:

2012

Language:

english

File:

PDF, 880 KB

english, 2012

5

Structure–activity relationships of pyrazole derivatives as potential therapeutics for immune thrombocytopenias

Purohit, Meena K., Chakka, Sai Kumar, Scovell, Iain, Neschadim, Anton, Bello, Angelica M., Salum, Noruê, Katsman, Yulia, Bareau, Madeleine C., Branch, Donald R., Kotra, Lakshmi P.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 2.89 MB

english, 2014

6

Small molecule inhibitors of phagocytosis for treatment of immune cytopenias

Branch, Donald, Purohit, Meena, Scovell, Iain, Neschadim, Anton, Katsman, Yulia, Kotra, Lakshmi

Journal:

Experimental Hematology

Year:

2013

Language:

english

File:

PDF, 47 KB

english, 2013

7

Disulfide linked pyrazole derivatives inhibit phagocytosis of opsonized blood cells

Purohit, Meena K., Scovell, Iain, Neschadim, Anton, Katsman, Yulia, Branch, Donald R., Kotra, Lakshmi P.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 504 KB

english, 2013

8

Relaxin receptor antagonist AT-001 synergizes with docetaxel in androgen-independent prostate xenografts

Neschadim, A., Pritzker, L. B., Pritzker, K. P. H., Branch, D. R., Summerlee, A. J. S., Trachtenberg, J., Silvertown, J. D.

Journal:

Endocrine Related Cancer

Year:

2014

Language:

english

File:

PDF, 430 KB

english, 2014

9

Autologous Transplantation of Lentivector/Acid Ceramidase–Transduced Hematopoietic Cells in Nonhuman Primates

Walia, Jagdeep S., Neschadim, Anton, Lopez-Perez, Orlay, Alayoubi, Abdulfatah, Fan, Xin, Carpentier, Stéphane, Madden, Melissa, Lee, Chyan-Jang, Cheung, Fred, Jaffray, David A., Levade, Thierry, McCar

Journal:

Human Gene Therapy

Year:

2011

Language:

english

File:

PDF, 1.84 MB

english, 2011

10

Therapeutic Effect of IVIG on Inflammatory Arthritis in Mice Is Dependent on the Fc Portion and Independent of Sialylation or Basophils

Campbell, I. K., Miescher, S., Branch, D. R., Mott, P. J., Lazarus, A. H., Han, D., Maraskovsky, E., Zuercher, A. W., Neschadim, A., Leontyev, D., McKenzie, B. S., Kasermann, F.

Journal:

The Journal of Immunology

Year:

2014

Language:

english

File:

PDF, 1.33 MB

english, 2014

11

Engineered human Tmpk fused with truncated cell-surface markers: versatile cell-fate control safety cassettes

Scaife, M, Pacienza, N, Au, B C Y, Wang, J C M, Devine, S, Scheid, E, Lee, C-J, Lopez-Perez, O, Neschadim, A, Fowler, D H, Foley, R, Medin, J A

Journal:

Year:

2013

Language:

english

File:

PDF, 2.55 MB

english, 2013

12

Analog of H2 relaxin exhibits antagonistic properties and impairs prostate tumor growth

Silvertown, J. D., Symes, J. C., Neschadim, A., Nonaka, T., Kao, J. C. H., Summerlee, A. J. S., Medin, J. A.

Journal:

The FASEB Journal

Year:

2007

Language:

english

File:

PDF, 618 KB

english, 2007

13

A New Pyrimidine-Specific Reporter Gene: A Mutated Human Deoxycytidine Kinase Suitable for PET During Treatment with Acycloguanosine-Based Cytotoxic Drugs

Likar, Y., Zurita, J., Dobrenkov, K., Shenker, L., Cai, S., Neschadim, A., Medin, J. A., Sadelain, M., Hricak, H., Ponomarev, V.

Journal:

Journal of Nuclear Medicine

Year:

2010

Language:

english

File:

PDF, 1.38 MB

english, 2010

14

Novel application of lentiviral vectors towards treatment of graft-versus-host disease

Scaife, Matthew D, Neschadim, Anton, Fowler, DH, Medin, JA

Journal:

Expert Opinion on Biological Therapy

Year:

2009

Language:

english

File:

PDF, 522 KB

english, 2009

15

Cell Fate Control Gene Therapy Based on Engineered Variants of Human Deoxycytidine Kinase

Neschadim, Anton, Wang, James CM, Sato, Takeya, Fowler, Daniel H, Lavie, Arnon, Medin, Jeffrey A

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 694 KB

english, 2012

16

Engineered Human tmpk/AZT As a Novel Enzyme/Prodrug Axis for Suicide Gene Therapy

Sato, Takeya, Neschadim, Anton, Konrad, Manfred, Fowler, Daniel H, Lavie, Arnon, Medin, Jeffrey A

Journal:

Molecular Therapy

Year:

2007

Language:

english

File:

PDF, 222 KB

english, 2007

17

Small molecule phagocytosis inhibitors for immune cytopenias

Neschadim, Anton, Kotra, Lakshmi P., Branch, Donald R.

Journal:

Autoimmunity Reviews

Year:

2016

Language:

english

File:

PDF, 506 KB

english, 2016

18

c-SRC protein tyrosine kinase regulates early HIV-1 infection post-entry

McCarthy, Stephen D.S., Sakac, Darinka, Neschadim, Anton, Branch, Donald R.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.13 MB

english, 2016

19

Targeting the relaxin hormonal pathway in prostate cancer

Neschadim, Anton, Summerlee, Alastair J.S., Silvertown, Joshua D.

Journal:

International Journal of Cancer

Year:

2015

Language:

english

File:

PDF, 287 KB

english, 2015

20

Cytokine profiles in mouse models of experimental immune thrombocytopenia reveal a lack of inflammation and differences in response to intravenous immunoglobulin depending on the mouse strain

Leontyev, Danila, Neschadim, Anton, Branch, Donald R.

Journal:

Transfusion (Elsevier)

Year:

2014

Language:

english

File:

PDF, 384 KB

english, 2014

21

Extracellular histones identified in crocodile blood inhibit in vitro HIV-1 infection

Kozlowski, Hannah N., Lai, Eric T.L., Havugimana, Pierre C., White, Carl, Emili, Andrew, Sakac, Darinka, Binnington, Beth, Neschadim, Anton, Mccarthy, Stephen D.S., Branch, Donald R.

Journal:

Year:

2016

Language:

english

File:

PDF, 463 KB

english, 2016

22

Engineering Hematopoietic Cells for Cancer Immunotherapy

Resetca, Diana, Neschadim, Anton, Medin, Jeffrey A.

Journal:

Journal of Immunotherapy

Year:

2016

Language:

english

File:

PDF, 353 KB

english, 2016

23

GM-CSF and IL-4 are not involved in IVIG-mediated amelioration of ITP in mice: a role for IL-11 cannot be ruled out

Lewis, Bonnie J.B., Leontyev, Danila, Neschadim, Anton, Blacquiere, Megan, Branch, Donald R.

Journal:

Clinical & Experimental Immunology

Year:

2018

Language:

english

File:

PDF, 1.35 MB

english, 2018

24

The Engineered Thymidylate Kinase (TMPK)/AZT Enzyme-Prodrug Axis Offers Efficient Bystander Cell Killing for Suicide Gene Therapy of Cancer

Sato, Takeya, Neschadim, Anton, Lavie, Arnon, Yanagisawa, Teruyuki, Medin, Jeffrey A., Najbauer, Joseph

Journal:

Year:

2013

Language:

english

File:

PDF, 1.54 MB

english, 2013

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